Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | EIF4E | P06730 | 10/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16535655 | 0.84 | EIF4E (0.39) | PTGER1MGAMGAASIMGAM2 | |
| SCHEMBL20197479 | 0.79 | EIF4E (0.39) | EIF4ENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL20197337 | 0.78 | CYP1A2 (0.40) | EIF4ENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL20197238 | 0.77 | CYP19A1 (0.44) | EIF4ENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL20197235 | 0.74 | SREBF2 (0.42) | KDM4ESREBF2MAPTATM | |
| SCHEMBL20197443 | 0.74 | C1S (0.39) | EIF4ENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL20197481 | 0.74 | EIF4E (0.37) | EIF4ENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL20197223 | 0.73 | SREBF2 (0.42) | KDM4ESREBF2MAPTATM | |
| SCHEMBL20197222 | 0.73 | KDM4E (0.37) | EIF4ENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL20197301 | 0.72 | KDM4E (0.34) | EIF4ENPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |