Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14616553 | 0.89 | MAPT (0.44) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL17231868 | 0.86 | MAPT (0.42) | MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL12679101 | 0.86 | MAPT (0.42) | MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL18037721 | 0.86 | MAPT (0.42) | MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL18037724 | 0.85 | FURIN (0.44) | MAPTKMT2AMEN1FURINALOX12 | |
| SCHEMBL25488668 | 0.84 | MEN1 (0.38) | MAPTKMT2AMEN1FURINALDH1A1 | |
| SCHEMBL14616552 | 0.83 | MAPT (0.39) | MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL14642912 | 0.82 | MAPT (0.39) | MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL15290542 | 0.82 | MAPT (0.39) | MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL13897310 | 0.82 | L3MBTL1 (0.43) | MAPTKMT2AMEN1ALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2917195-B9 | SPLICEOSTATIN ANALOGS | PFIZER (US) | 2018-05-30 | — | — | EP | disclosed |