Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FURIN | P09958 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20197999 | 0.84 | MAPT (0.43) | MEN1KMT2AL3MBTL1RAD52FURIN | |
| SCHEMBL18037724 | 0.81 | FURIN (0.44) | MEN1KMT2AL3MBTL1GAAFURIN | |
| SCHEMBL14616553 | 0.80 | MAPT (0.44) | MEN1KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL17231868 | 0.78 | MAPT (0.42) | MEN1KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL12679101 | 0.78 | MAPT (0.42) | MEN1KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL18037721 | 0.78 | MAPT (0.42) | MEN1KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL13897310 | 0.77 | L3MBTL1 (0.43) | MEN1KMT2AL3MBTL1GAAMAPT | |
| SCHEMBL21098957 | 0.77 | L3MBTL1 (0.43) | MEN1KMT2AL3MBTL1GAAMAPT | |
| SCHEMBL14616552 | 0.75 | MAPT (0.39) | MEN1KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL15290542 | 0.74 | MAPT (0.39) | MEN1KMT2AGAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088236-A1 | BICYCLIC PEPTIDE LIGAND OF MT1-MMP AND CONJUGATE THEREOF | 海思科医药集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |