Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25124098 | 0.86 | CA14 (0.39) | CA14CA12CA1CA7HDAC1 | |
| SCHEMBL1027531 | 0.86 | AAK1 (0.34) | AAK1CA14CA12CA1CA7 | |
| SCHEMBL20248816 | 0.83 | CTSK (0.35) | CA14CA12CA1CA7HDAC1 | |
| SCHEMBL18658421 | 0.82 | HDAC6 (0.34) | CA14CA12CA1CA7HDAC1 | |
| SCHEMBL18419554 | 0.82 | HDAC6 (0.34) | CA14CA12CA1CA7HDAC1 | |
| SCHEMBL18281954 | 0.82 | CTSS (0.34) | CA14CA12CA1CA7HDAC1 | |
| SCHEMBL20198186 | 0.80 | CA14 (0.37) | AAK1CA14CA12CA1CA7 | |
| SCHEMBL6673738 | 0.80 | GABRR1 (0.33) | AAK1CA14HDAC1HDAC2HDAC6 | |
| SCHEMBL14063006 | 0.79 | HDAC6 (0.36) | AAK1CA14HDAC1HDAC2HDAC6 | |
| SCHEMBL24525561 | 0.79 | ALDH1A1 (0.40) | AAK1CA14CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3326627-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2018-05-30 | — | — | EP | disclosed |