Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017368 | 0.80 | HDAC6 (0.55) | ALDH1A1PKMMEN1KMT2ARECQL | |
| SCHEMBL12102425 | 0.80 | HDAC6 (0.66) | ALDH1A1PKMMEN1KMT2ARECQL | |
| SCHEMBL370910 | 0.78 | NPC1 (0.43) | ALDH1A1PKMMEN1KMT2ARECQL | |
| SCHEMBL29988753 | 0.78 | HDAC6 (0.63) | ALDH1A1PKMMEN1KMT2ARECQL | |
| SCHEMBL15199000 | 0.78 | HDAC6 (0.63) | ALDH1A1PKMMEN1KMT2ARECQL | |
| SCHEMBL24754664 | 0.76 | BRD4 (0.41) | ALDH1A1PKMMEN1KMT2ARECQL | |
| SCHEMBL29184736 | 0.76 | BRD4 (0.41) | ALDH1A1PKMMEN1KMT2ARECQL | |
| SCHEMBL29184721 | 0.76 | BRD4 (0.41) | ALDH1A1PKMMEN1KMT2ARECQL | |
| SCHEMBL12388321 | 0.75 | NPC1 (0.50) | ALDH1A1PKMHDAC6NPC1RAB9A | |
| SCHEMBL28021103 | 0.75 | KDM4E (0.42) | ALDH1A1PKMMEN1KMT2AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376394-B2 | Preparation of bendamustine and its salts | DR. REDDY'S LABORATORIES LTD. (IN) | 2016-06-28 | — | — | US | disclosed |
| US-20130217888-A1 | PROCESS FOR PREPARING BENDAMUS TINE HYDROCHLORIDE MONOHYDRATE | SHAILPA MEDICARE LIMITED (IN) | 2013-08-22 | — | — | US | disclosed |
| US-20130158273-A1 | PREPARATION OF BENDAMUSTINE AND ITS SALTS | DR. REDDY'S LABORATORIES, INC. (US) | 2013-06-20 | — | — | US | disclosed |
| EP-2516404-A2 | PREPARATION OF BENDAMUSTINE AND ITS SALTS | Dr. Reddy's Laboratories Ltd. (IN) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011079193-A2 | PREPARATION OF BENDAMUSTINE AND ITS SALTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158273-A1 | PREPARATION OF BENDAMUSTINE AND ITS SALTS | FOLR1, FOLR2, FLT3 | ALDH1A1 746/4885PKM 1325/4885MEN1 1297/4885 |
| US-20130217888-A1 | PROCESS FOR PREPARING BENDAMUS TINE HYDROCHLORIDE MONOHYDRATE | FLT3, TYMP, SBDS | ALDH1A1 1939/4885PKM 837/4885MEN1 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.