Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22131988 | 0.98 | HPGD (0.39) | HPGDLMNAMEN1KMT2AMAPT | |
| SCHEMBL24864982 | 0.89 | CA2 (0.34) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL17849096 | 0.83 | LMNA (0.33) | LMNA | |
| SCHEMBL21318647 | 0.79 | POLB (0.35) | HPGDKMT2AMAPTPOLBKDM4E | |
| SCHEMBL12949344 | 0.79 | LMNA (0.30) | LMNA | |
| SCHEMBL23509809 | 0.79 | KDM4E (0.32) | LMNAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL26078770 | 0.78 | ESR1 (0.40) | HPGDMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL20961493 | 0.77 | MAPT (0.35) | HPGDLMNAMEN1KMT2AMAPT | |
| SCHEMBL14461267 | 0.77 | LMNA (0.33) | LMNAMEN1KMT2AESR1 | |
| SCHEMBL4403188 | 0.77 | HPGD (0.61) | HPGDLMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675930-B1 | NEW MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF | MERCK PATENT GMBH (DE) | 2018-05-30 | — | — | EP | disclosed |