SCHEMBL24864982

SCHEMBL24864982

O=P(C1=CC=CCC1)(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA5A P35218 1/20 0.34
LMNA P02545 1/20 0.33
CFTR P13569 1/20 0.31
NPSR1 Q6W5P4 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
ALPG P10696 1/20 0.31
ALOX12 P18054 1/20 0.31
NPY1R P25929 1/20 0.31
HTT P42858 1/20 0.31
NPY2R P49146 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22131988 0.91 HPGD (0.39) LMNANPSR1ALDH1A1GAAMAPT
SCHEMBL20198236 0.89 HPGD (0.38) LMNANPSR1ALDH1A1GAAMAPT
SCHEMBL17849096 0.87 LMNA (0.33) LMNA
SCHEMBL21318647 0.85 POLB (0.35) CA2CA4L3MBTL1ALDH1A1GAA
SCHEMBL26078770 0.84 ESR1 (0.40) CA2CA4CA5ACFTRNPSR1
SCHEMBL13272098 0.83
SCHEMBL22132691 0.82 ALDH1A1 (0.43) NPSR1ALDH1A1HTTMEN1KMT2A
SCHEMBL22416842 0.82 CA2 (0.32) CA2CA4CA5A
SCHEMBL5557998 0.82 CA2 (0.32) CA2CA4CA5ANPSR1GAA
SCHEMBL12949344 0.82 LMNA (0.30) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023282236-A1 RARE EARTH COMPLEX 東ソー株式会社 2023-01-12 WO disclosed