Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12283588 | 0.93 | ACHE (0.48) | ACHELMNATSHRALOX12RAB9A | |
| SCHEMBL20198275 | 0.93 | ACHE (0.48) | ACHELMNATSHRALOX12RAB9A | |
| SCHEMBL3289166 | 0.93 | ACHE (0.48) | ACHELMNATSHRALOX12RAB9A | |
| SCHEMBL3289160 | 0.91 | ACHE (0.42) | ACHELMNARAB9ANPC1HPRT1 | |
| SCHEMBL4401181 | 0.91 | ACHE (0.42) | ACHELMNARAB9ANPC1HPRT1 | |
| SCHEMBL12336913 | 0.89 | ALDH1A1 (0.42) | TDP1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8772023 | 0.86 | ALDH1A1 (0.47) | LMNATSHRTDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2785940 | 0.84 | ALDH1A1 (0.50) | TDP1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL235851 | 0.83 | ACHE (0.50) | ACHELMNATSHRALOX12TDP1 | |
| SCHEMBL4401131 | 0.83 | ACHE (0.50) | ACHELMNATSHRALOX12TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675930-B1 | NEW MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF | MERCK PATENT GMBH (DE) | 2018-05-30 | — | — | EP | disclosed |