SCHEMBL4401181

SCHEMBL4401181

Cc1ccc([S+]([O-])c2ccc(-c3ccc([S+]([O-])c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.42
TDP1 Q9NUW8 1/20 0.42
PKM P14618 1/20 0.35
GAA P10253 1/20 0.35
ENPP3 O14638 1/20 0.34
ENPP1 P22413 1/20 0.34
KIF11 P52732 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
NPC1 O15118 3/20 0.32
RAB9A P51151 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3289160 1.00 ACHE (0.42) ACHETDP1PKMGAAENPP3
SCHEMBL235851 0.92 ACHE (0.50) ACHETDP1GAAALDH1A1HSD17B10
SCHEMBL4401131 0.92 ACHE (0.50) ACHETDP1GAAALDH1A1HSD17B10
SCHEMBL20198276 0.91 ACHE (0.42) ACHETDP1ALDH1A1HPGDNPC1
SCHEMBL14137628 0.84 PTGS2 (0.54)
SCHEMBL20661294 0.82 ACHE (0.40) ACHETDP1PKMGAAENPP3
SCHEMBL20198275 0.82 ACHE (0.48) ACHETDP1GAAKIF11ALDH1A1
SCHEMBL20661295 0.82 ACHE (0.40) ACHETDP1PKMGAAENPP3
SCHEMBL12283588 0.82 ACHE (0.48) ACHETDP1GAAKIF11ALDH1A1
SCHEMBL3289166 0.82 ACHE (0.48) ACHETDP1GAAKIF11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173276-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2012-05-08 US disclosed
US-20100102305-A1 MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2010-04-29 US disclosed
US-7659540-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2010-02-09 US disclosed
US-20070080343-A1 New materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2007-04-12 US disclosed