Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.50 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20198312 | 0.96 | MAOA (0.44) | MAOAMAOBBCL2MCL1MAPT | |
| SCHEMBL15498442 | 0.94 | MAOA (0.55) | MAOAMAOBBCL2MCL1MAPT | |
| SCHEMBL29591921 | 0.82 | MAOA (0.47) | MAOAMAOBBCL2MCL1MAPT | |
| SCHEMBL16882976 | 0.82 | ESR1 (0.46) | MAOAMAOBBCL2MCL1MAPT | |
| SCHEMBL19654607 | 0.81 | MAOA (0.46) | MAOAMAOBBCL2MCL1MAPT | |
| SCHEMBL25052760 | 0.79 | KDM4E (0.41) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL23372165 | 0.78 | PDE7A (0.35) | MAOAMAOBMAPTMEN1KMT2A | |
| SCHEMBL16882977 | 0.78 | PDE4D (0.43) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL28991408 | 0.78 | MAOA (0.42) | MAOAMAOBBCL2MCL1MAPT | |
| SCHEMBL19773709 | 0.78 | KDM4E (0.40) | MAPTMEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140061545-A1 | BIS(SULFONYL)BIARYL DERIVATIVES AS ELECTRON TRANSPORTING AND/OR HOST MATERIALS | GEORGIA TECH RESEARCH CORPORATION | 2014-03-06 | — | — | US | disclosed |
| US-20140061545-A1 | BIS(SULFONYL)BIARYL DERIVATIVES AS ELECTRON TRANSPORTING AND/OR HOST MATERIALS | GEORGIA TECH RESEARCH CORPORATION | 2014-03-06 | — | — | US | disclosed |
| EP-2649150-A2 | BIS(SULFONYL)BIARYL DERIVATIVES AS ELECTRON TRANSPORTING AND/OR HOST MATERIALS | Georgia Tech Research Corporation (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012078770-A2 | BIS(SULFONYL)BIARYL DERIVATIVES AS ELECTRON TRANSPORTING AND/OR HOST MATERIALS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |