SCHEMBL755432

SCHEMBL755432

C1=CC(=Nc2ccccc2)C=CC1=Nc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
MAPT P10636 4/20 0.40
KDM4E B2RXH2 1/20 0.40
MPI P34949 1/20 0.40
CACNA1B Q00975 1/20 0.40
APBA1 Q02410 1/20 0.40
HTT P42858 2/20 0.38
MIF P14174 1/20 0.38
MAPK1 P28482 1/20 0.38
HTR3E A5X5Y0 1/20 0.38
SLC22A2 O15244 1/20 0.38
SLC22A1 O15245 1/20 0.38
SLC22A3 O75751 1/20 0.38
HTR3B O95264 1/20 0.38
PLAU P00749 1/20 0.38
HTR3A P46098 1/20 0.38
HTR3D Q70Z44 1/20 0.38
HTR3C Q8WXA8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15463133 0.92 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL12336906 0.88 ALDH1A1 (0.43) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL6208251 0.87 ALDH1A1 (0.38) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL3313983 0.87 ALDH1A1 (0.38) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL13871377 0.87 ALDH1A1 (0.38) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL11273533 0.87 ALDH1A1 (0.38) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL1813567 0.87 TXNRD1 (0.47) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL6152341 0.87 ALDH1A1 (0.38) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL20683979 0.85 ALDH1A1 (0.36) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL20198346 0.85 ALOX12 (0.43) ALDH1A1MEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325078-A Preparation method and application of benzoquinone conjugated polymer 中国科学院宁波材料技术与工程研究所 2024-07-12 CN claimed
US-6376728-B1 OF ALKENYL MONOMERS HERCULES INCORPORATED 2002-04-23 US claimed
JP-62131028-A None JP disclosed
JP-8208581-A None JP disclosed
CN-118325078-A Preparation method and application of benzoquinone conjugated polymer 中国科学院宁波材料技术与工程研究所 2024-07-12 CN disclosed
EP-3906245-B1 MULTIFUNCTIONAL ORGANOSILICON COMPOUND AND RELATED METHODS, COMPOUNDS, AND COMPOSITIONS DOW SILICONES CORP (US) 2024-05-29 EP disclosed
EP-3854610-B1 PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2024-04-17 EP disclosed
US-11820846-B2 Composition, method of preparing copolymer, and methods and end uses thereof DOW SILICONES CORPORATION (US) 2023-11-21 US disclosed
WO-2023201154-A1 SILICONE - VINYLESTER FUNCTIONAL COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN PERSONAL CARE COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-19 WO disclosed
WO-2023201146-A1 PREPARATION OF ORGANOSILICON COMPOUNDS WITH VINYLESTER FUNCTIONALITY DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-19 WO disclosed
US-20230295193-A1 PREPARATION OF MULTIFUNCTIONAL ORGANOSILICON COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC 2023-09-21 US disclosed
EP-0497379-A1 Organic polymer solution NITTO DENKO CORPORATION (JP) 1992-08-05 EP disclosed
US-5109907-A Tire treads with reduced rolling resistance BRIDGESTONE/FIRESTONE, INC. (US) 1992-05-05 US disclosed
EP-0479578-A1 Color-forming recording material MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-04-08 EP disclosed
US-5079096-A And a magnetic layer formed on it; low surface smoothness and resistance HITACHI MAXELL, LTD. (JP) 1992-01-07 US disclosed
US-5066729-A Tire Treads BRIDGESTONE/FIRESTONE, INC. (US) 1991-11-19 US disclosed
EP-0451604-A2 Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines BRIDGESTONE/FIRESTONE, INC. (US) 1991-10-16 EP disclosed
EP-0361429-A2 Organic polymer, conducting organic polymer, production methods and uses of the same NITTO DENKO CORPORATION (JP) 1990-04-04 EP disclosed
JP-S62131028-A PRODUCTION OF ANILINE POLYMER AGENCY OF IND SCIENCE & TECHNOL 1987-06-13 JP disclosed
US-3978161-A METALLIC SODIUM, UNSATURATED HYDROCARBON POLYMER, TERT-AMINE CHELATING AGENT THE GENERAL TIRE & RUBBER COMPANY (US) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11820846-B2 Composition, method of preparing copolymer, and methods and end uses thereof BRS3, OXSR1, OXER1 ALDH1A1 3354/4885MEN1 348/4885KMT2A 4700/4885
US-20230295193-A1 PREPARATION OF MULTIFUNCTIONAL ORGANOSILICON COMPOUNDS SI, CEL, VIP ALDH1A1 988/4885MEN1 239/4885KMT2A 1970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.