Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2019447 | 0.84 | ALDH1A1 (0.47) | MAOBALDH1A1CYP1A1CYP1B1PPARD | |
| SCHEMBL4773642 | 0.80 | MAPT (0.48) | MAOBALDH1A1 | |
| SCHEMBL4773647 | 0.80 | MAPT (0.48) | MAOBALDH1A1 | |
| SCHEMBL578331 | 0.79 | MTNR1A (0.58) | — | |
| SCHEMBL16379339 | 0.78 | PPARA (0.49) | MAOBALDH1A1PPARDPPARAPSMB5 | |
| SCHEMBL19649431 | 0.78 | MAPT (0.41) | MAOB | |
| SCHEMBL27665176 | 0.77 | LMNA (0.58) | MAOBALDH1A1PPARD | |
| SCHEMBL27710429 | 0.77 | LMNA (0.58) | MAOBALDH1A1PPARD | |
| SCHEMBL9713337 | 0.77 | MTNR1A (0.53) | PPARDPPARA | |
| SCHEMBL9713332 | 0.77 | MTNR1A (0.53) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075522-A1 | PRODRUG COMPOUNDS USEFUL AS CANNABINOID LIGANDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | WO | disclosed |