Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177765 | 0.81 | TSHR (0.36) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL3666505 | 0.79 | TSHR (0.38) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL20079310 | 0.77 | HMGCR (0.39) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL7158382 | 0.74 | TSHR (0.40) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL4590512 | 0.74 | TSHR (0.40) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27546906 | 0.74 | TSHR (0.32) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL28024883 | 0.73 | TSHR (0.33) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1374290 | 0.72 | ALDH1A1 (0.47) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL302801 | 0.72 | THRB (0.43) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27814320 | 0.72 | TSHR (0.39) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2923692-B1 | Beta-amino ester compounds and uses thereof | LIVING PROOF INC (US) | 2018-05-30 | — | — | EP | disclosed |