Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884328 | 0.79 | SMN1; SMN2 (0.51) | MAPTKDM4ELMNANPC1ALDH1A1 | |
| SCHEMBL9324010 | 0.69 | TP53 (0.44) | KMT2AMEN1DHODHKDM4ELMNA | |
| SCHEMBL27662263 | 0.69 | TP53 (0.41) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL5261281 | 0.69 | ALOX5 (0.46) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL259469 | 0.69 | GAA (0.51) | KMT2AKDM4EALDH1A1GAAHPGD | |
| SCHEMBL7489817 | 0.68 | JAK2 (0.52) | MAPTKDM4ELMNANPC1ALDH1A1 | |
| SCHEMBL4243696 | 0.66 | MAP2K3 (0.47) | KMT2AMEN1DHODHMAPTKDM4E | |
| SCHEMBL858475 | 0.66 | HTT (0.53) | KMT2AMEN1DHODHMAPTKDM4E | |
| SCHEMBL28750125 | 0.66 | ALDH1A1 (0.49) | MAPTKDM4ELMNANPC1ALDH1A1 | |
| SCHEMBL11177529 | 0.66 | AKT1 (0.43) | KMT2AMEN1MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098411-A1 | GSK-3 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-31 | — | — | WO | disclosed |