Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27662263 | 0.89 | TP53 (0.41) | TP53ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL4243696 | 0.85 | MAP2K3 (0.47) | TP53ALDH1A1KDM4ERAB9AMEN1 | |
| SCHEMBL27515966 | 0.84 | KMO (0.51) | ALDH1A1KDM4ELMNAKMORAB9A | |
| SCHEMBL10622534 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KDM4ESMN1; SMN2LMNALDHA | |
| SCHEMBL28794429 | 0.84 | MCL1 (0.49) | MCL1 | |
| SCHEMBL8822098 | 0.81 | PDGFRB (0.38) | TP53ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL11177529 | 0.81 | AKT1 (0.43) | TP53ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL259469 | 0.81 | GAA (0.51) | ALDH1A1KDM4ESMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL14736658 | 0.80 | ADORA3 (0.40) | ALDH1A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL21336547 | 0.78 | MEN1 (0.38) | ALDH1A1KDM4ELMNARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978069-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-31 | — | — | US | claimed |
| CN-1088062-C | Certain 4 -aminomethyl -2 -substituted imidazole derivatives and 2 -aminomethyl -4 -substituted imidazole derivatives, new classes of dopamine receptor subtype specific ligands | NEUROGEN CORP (US) | 2002-07-24 | — | — | CN | disclosed |
| CN-1177349-A | Certain 4 -aminomethyl -2 -substituted imidazole derivatives and 2 -aminomethyl -4 -substituted imidazole derivatives, new classes of dopamine receptor subtype specific ligands | NEUROGEN CORP (US) | 1998-03-25 | — | — | CN | disclosed |
| EP-0365030-B1 | Imidazole compound and process for preparing the same | ISHIHARA SANGYO KAISHA (JP) | 1994-01-26 | — | — | EP | disclosed |
| US-5023336-A | Fungicides, biocides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1991-06-11 | — | — | US | disclosed |
| EP-0365030-A1 | Imidazole compound and process for preparing the same | ISHIHARA SANGYO KAISHA, Ltd. (JP) | 1990-04-25 | — | — | EP | disclosed |