SCHEMBL20199524

SCHEMBL20199524

N#Cc1ccc(-n2c3ccccc3c3c4c(ccc32)C2(c3ccccc3-4)c3ccccc3C3(c4ccccc4-c4ccccc43)c3ccccc32)cc1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PGR P06401 6/20 0.36
USP14 P54578 2/20 0.34
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PDK2 Q15119 2/20 0.31
RPS6KB1 P23443 1/20 0.30
GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20199803 0.89 KDM4E (0.41) KDM4EATML3MBTL1
SCHEMBL21578782 0.89 KDM4E (0.40) KDM4EATML3MBTL1
SCHEMBL20199516 0.87 L3MBTL1 (0.45) PGRKDM4EATML3MBTL1
SCHEMBL20199518 0.85 L3MBTL1 (0.37) KDM4EATML3MBTL1
SCHEMBL20199523 0.85 L3MBTL1 (0.34) PGRKDM4EATML3MBTL1
SCHEMBL20203669 0.84 PGR (0.36) PGRUSP14KDM4EATML3MBTL1
SCHEMBL25681016 0.83 L3MBTL1 (0.38) KDM4EATML3MBTL1
SCHEMBL22141038 0.83 KDM4E (0.35) KDM4EATML3MBTL1
SCHEMBL20199536 0.83 KDM4E (0.42) KDM4EATML3MBTL1
SCHEMBL23184506 0.83 PGR (0.33) PGRUSP14RPS6KB1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11001752-B2 Double spiro organic compound and organic electronic element comprising same LG CHEM, LTD. (KR) 2021-05-11 US disclosed
US-20180148640-A1 DOUBLE SPIRO ORGANIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-31 US disclosed
US-20180148640-A1 DOUBLE SPIRO ORGANIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11001752-B2 Double spiro organic compound and organic electronic element comprising same DCX, TERT, TELO2 PGR 1569/4885USP14 3722/4885KDM4E 1392/4885
US-20180148640-A1 DOUBLE SPIRO ORGANIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME DCX, TERT, TELO2 PGR 1569/4885USP14 3722/4885KDM4E 1392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.