SCHEMBL20199993

SCHEMBL20199993

c1ccc2c(c1)Oc1cc(-c3ccccc3-c3cc4c5c(c3)Oc3ccccc3N5c3ccccc3O4)cc3c1N2c1ccccc1O3

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 13/20 0.38
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ALOX5 P09917 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
ATM Q13315 1/20 0.32
P2RX1 P51575 2/20 0.31
P2RX3 P56373 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22958660 0.92 MGLL (0.37) P2RX4MAPTSMN1; SMN2NPSR1
SCHEMBL15489910 0.90 P2RX4 (0.41) P2RX4MAPTSMN1; SMN2NPSR1ALOX5
SCHEMBL30721161 0.90 P2RX4 (0.41) P2RX4MAPTSMN1; SMN2NPSR1ALOX5
SCHEMBL30822885 0.90 P2RX4 (0.41) P2RX4MAPTSMN1; SMN2NPSR1ALOX5
SCHEMBL22958716 0.89 MGLL (0.37) P2RX4MAPTSMN1; SMN2NPSR1
SCHEMBL22958767 0.88 MGLL (0.34) P2RX4MAPTSMN1; SMN2NPSR1
SCHEMBL15489957 0.87 P2RX4 (0.39) P2RX4MAPTSMN1; SMN2NPSR1ALOX5
SCHEMBL24390100 0.85 MAPT (0.30) MAPTSMN1; SMN2NPSR1
SCHEMBL22958662 0.85 ESR1 (0.38) MAPTSMN1; SMN2NPSR1ALOX5KDM4E
SCHEMBL26310807 0.85 PTPRC (0.40) P2RX4MAPTSMN1; SMN2NPSR1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11088207-B2 Solid-state image sensor, photoelectric conversion film, electron blocking layer, imaging apparatus, and electronic device SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2021-08-10 US disclosed
US-20180151625-A1 SOLID-STATE IMAGE SENSOR, PHOTOELECTRIC CONVERSION FILM, ELECTRON BLOCKING LAYER, IMAGING APPARATUS, AND ELECTRONIC DEVICE SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2018-05-31 US disclosed
US-20180151625-A1 SOLID-STATE IMAGE SENSOR, PHOTOELECTRIC CONVERSION FILM, ELECTRON BLOCKING LAYER, IMAGING APPARATUS, AND ELECTRONIC DEVICE SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180151625-A1 SOLID-STATE IMAGE SENSOR, PHOTOELECTRIC CONVERSION FILM, ELECTRON BLOCKING LAYER, IMAGING APPARATUS, AND ELECTRONIC DEVICE EMC1, EMC2, ESR1 P2RX4 4108/4885MAPT 1073/4885SMN1; SMN2 3905/4885
US-11088207-B2 Solid-state image sensor, photoelectric conversion film, electron blocking layer, imaging apparatus, and electronic device EMC1, EMC2, ESR1 P2RX4 4108/4885MAPT 1073/4885SMN1; SMN2 3905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.