SCHEMBL20199997

SCHEMBL20199997

c1ccc(-n2c3ccc(-c4ccc5c(c4)Oc4cccc6c4N5c4ccccc4O6)cc3c3cc(-c4ccc5c(c4)Oc4cccc6c4N5c4ccccc4O6)ccc32)cc1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
EDNRA P25101 5/20 0.35
EDNRB P24530 1/20 0.33
P2RX4 Q99571 1/20 0.33
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20199987 0.97 KDM4E (0.34) KDM4EATML3MBTL1EDNRAEDNRB
SCHEMBL22958736 0.97 ATM (0.34) KDM4EATML3MBTL1EDNRAEDNRB
SCHEMBL22958684 0.97 ATM (0.34) KDM4EATML3MBTL1EDNRAEDNRB
SCHEMBL22958722 0.96 L3MBTL1 (0.43) KDM4EATML3MBTL1EDNRAEDNRB
SCHEMBL22958792 0.94 L3MBTL1 (0.45) KDM4EATML3MBTL1EDNRAEDNRB
SCHEMBL22958756 0.93 L3MBTL1 (0.42) KDM4EATML3MBTL1EDNRAEDNRB
SCHEMBL10331571 0.92 KDM4E (0.38) KDM4EATML3MBTL1EDNRAEDNRB
SCHEMBL19035949 0.92 KDM4E (0.41) KDM4EATML3MBTL1EDNRAEDNRB
SCHEMBL22958670 0.91 ATM (0.35) KDM4EATML3MBTL1EDNRAEDNRB
SCHEMBL22958661 0.91 ATM (0.35) KDM4EATML3MBTL1EDNRAEDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11088207-B2 Solid-state image sensor, photoelectric conversion film, electron blocking layer, imaging apparatus, and electronic device SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2021-08-10 US disclosed
US-20180151625-A1 SOLID-STATE IMAGE SENSOR, PHOTOELECTRIC CONVERSION FILM, ELECTRON BLOCKING LAYER, IMAGING APPARATUS, AND ELECTRONIC DEVICE SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2018-05-31 US disclosed
US-20180151625-A1 SOLID-STATE IMAGE SENSOR, PHOTOELECTRIC CONVERSION FILM, ELECTRON BLOCKING LAYER, IMAGING APPARATUS, AND ELECTRONIC DEVICE SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180151625-A1 SOLID-STATE IMAGE SENSOR, PHOTOELECTRIC CONVERSION FILM, ELECTRON BLOCKING LAYER, IMAGING APPARATUS, AND ELECTRONIC DEVICE EMC1, EMC2, ESR1 KDM4E 776/4885ATM 1626/4885L3MBTL1 2870/4885
US-11088207-B2 Solid-state image sensor, photoelectric conversion film, electron blocking layer, imaging apparatus, and electronic device EMC1, EMC2, ESR1 KDM4E 776/4885ATM 1626/4885L3MBTL1 2870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.