Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20188998 | 0.85 | KDM4E (0.48) | KDM4EMDM2ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL20200037 | 0.85 | BLM (0.35) | KDM4EMDM2ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL20199971 | 0.84 | ALDH1A1 (0.35) | KDM4EMDM2ALDH1A1SIGMAR1 | |
| SCHEMBL20200029 | 0.84 | ALDH1A1 (0.33) | KDM4EMDM2ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL29834060 | 0.84 | KDM4E (0.47) | KDM4EMDM2ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL23656479 | 0.82 | KMT2A (0.37) | KDM4EMDM2ALDH1A1KMT2AMEN1 | |
| SCHEMBL20200052 | 0.81 | ALDH1A1 (0.37) | KDM4EMDM2ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL20187612 | 0.80 | KDM4E (0.44) | KDM4EMDM2ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL20199982 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KMT2ASIGMAR1MEN1POLB | |
| SCHEMBL20199840 | 0.78 | TACR1 (0.32) | ALDH1A1KMT2AMEN1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544964-B1 | HIGH RELAXIVITY GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | Bayer Pharma AG (DE) | 2020-06-17 | — | — | EP | disclosed |
| WO-2018096082-A1 | HIGH RELAXIVITY GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-31 | — | — | WO | disclosed |