Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20199971 | 0.89 | ALDH1A1 (0.35) | HSD17B10SIGMAR1KDM4EMDM2TDP1 | |
| SCHEMBL20200027 | 0.89 | HSD17B10 (0.39) | BLMPMP22HSD17B10SIGMAR1KDM4E | |
| SCHEMBL20200024 | 0.85 | KDM4E (0.43) | SIGMAR1KDM4EMDM2ALDH1A1KMT2A | |
| SCHEMBL20187593 | 0.84 | BLM (0.35) | BLMPMP22HSD17B10SIGMAR1KDM4E | |
| SCHEMBL20199969 | 0.79 | SIGMAR1 (0.35) | BLMPMP22HSD17B10SIGMAR1KDM4E | |
| SCHEMBL20200029 | 0.78 | ALDH1A1 (0.33) | SIGMAR1KDM4EMDM2ALDH1A1TACR1 | |
| SCHEMBL20187613 | 0.78 | SIGMAR1 (0.34) | SIGMAR1KDM4EMDM2ALDH1A1 | |
| SCHEMBL20200038 | 0.77 | KDM4E (0.39) | HSD17B10SIGMAR1KDM4EMDM2TDP1 | |
| SCHEMBL22069374 | 0.77 | KDM4E (0.34) | SIGMAR1KDM4EMDM2TDP1ALDH1A1 | |
| SCHEMBL22112107 | 0.76 | BCL9 (0.43) | KDM4ETDP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096082-A1 | HIGH RELAXIVITY GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-31 | — | — | WO | disclosed |