SCHEMBL2020128

SCHEMBL2020128

CCC(Cl)P(=O)(O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9307304 0.78
SCHEMBL10620422 0.75 LAP3 (0.33)
SCHEMBL28848077 0.74 FDPS (0.36)
SCHEMBL27739877 0.74 FDPS (0.60)
SCHEMBL8583414 0.73 GABBR2 (0.42)
SCHEMBL2141213 0.73
Phosphoric Acid SCHEMBL27897703 0.73 LAP3 (0.43)
SCHEMBL10888965 0.73
SCHEMBL9493001 0.72 FDPS (0.61)
SCHEMBL10344310 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107011384-B A kind of preparation method of ring-type propyl phosphonous acid acid anhydride 中节能万润股份有限公司 2019-02-15 CN claimed
CN-118055676-A Hole transport material, application thereof, solar cell and preparation method thereof 天合光能股份有限公司 2024-05-17 CN disclosed
CN-107011384-B A kind of preparation method of ring-type propyl phosphonous acid acid anhydride 中节能万润股份有限公司 2019-02-15 CN disclosed
CN-107011384-B A kind of preparation method of ring-type propyl phosphonous acid acid anhydride 中节能万润股份有限公司 2019-02-15 CN disclosed
WO-2015053980-A1 PREPARATION OF ORGANOPHOSPHATE PEPTIDE ADDUCTS BATTELLE MEMORIAL INSTITUTE (US) 2015-04-16 WO disclosed
US-20150099864-A1 PREPARATION OF ORGANOPHOSPHATE PEPTIDE ADDUCTS BATTELLE MEMORIAL INSTITUTE 2015-04-09 US disclosed
US-20140243290-A1 Aminopyrimidines as SYK Inhibitors ALTMAN MICHAEL D (US) 2014-08-28 US disclosed
US-8759366-B2 Aminopyrimidines as SYK inhibitors MERCK SHARP & DOHME CORP. (US) 2014-06-24 US disclosed
CN-102295778-B Hyperbranched polyphosphoramidate and preparation method thereof UNIV XI AN JIAOTONG 2013-11-06 CN disclosed
US-8551984-B2 Aminopyrimidines as SYK inhibitors MERCK SHARP & DOHME CORP. (US) 2013-10-08 US disclosed
WO-2011075515-A1 AMINOPYRIMIDINES AS SYK INHIBITORS MERCK SHARP & DOHME CORP. (US) 2011-06-23 WO disclosed
EP-0682535-B1 New materials comprising achiral glyceryl phosphatidyl choline analogues BIOCOMPATIBLES LTD (GB) 1999-08-04 EP disclosed
US-5717047-A Materials BIOCOMPATIBLES LIMITED (GB) 1998-02-10 US disclosed
EP-0682535-A1 NEW MATERIALS BIOCOMPATIBLES LIMITED (GB) 1995-11-22 EP disclosed
WO-1994016748-A1 NEW MATERIALS BIOCOMPATIBLES LIMITED (GB) 1994-08-04 WO disclosed
EP-0244459-B1 PROCESS FOR THE PRODUCTION OF ALIPHATIC PHOSPHONIC ACIDS RHONE POULENC NEDERLAND B.V. (NL) 1990-02-07 EP disclosed
US-4728466-A TWO-STAGE SAPONIFICATION OF ESTER, CONTINUOUS REPLACEMENT RHONE-POULENC NEDERLAND B.V. (NL) 1988-03-01 US disclosed
US-4605647-A ANTITUMOR AGENTS; ANTICARCINOGENIC AGENTS ADIR, S.A.R.L. (FR) 1986-08-12 US disclosed
US-4319913-A Substituted benzazaphospholes, herbicidal compositions and the use thereof MONSANTO COMPANY (US) 1982-03-16 US disclosed
US-4064163-A REACTING DIESTER OF THE PHOSPHONIC ACID WITH HYDROGEN HALIDE AMCHEM PRODUCTS, INC. 1977-12-20 US disclosed