Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18048512 | 0.78 | ENO1 (1.00) | ENO1 | |
| SCHEMBL18077405 | 0.78 | ENO1 (1.00) | ENO1 | |
| SCHEMBL16447229 | 0.76 | ENO1 (0.44) | ENO1 | |
| SCHEMBL19749988 | 0.70 | — | — | |
| SCHEMBL21064227 | 0.70 | — | — | |
| SCHEMBL18947476 | 0.69 | KMT2A (0.33) | ENO1KMT2A | |
| SCHEMBL22810901 | 0.69 | KMT2A (0.33) | ENO1KMT2A | |
| SCHEMBL23280514 | 0.68 | — | — | |
| SCHEMBL19116254 | 0.68 | — | — | |
| SCHEMBL24504184 | 0.68 | ENO1 (0.62) | ENO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180147219-A1 | ENOLASE INHIBITORS AND METHODS OF TREATMENT THEREWITH | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180147219-A1 | ENOLASE INHIBITORS AND METHODS OF TREATMENT THEREWITH | ENO1, ECE1, ECI1 | ENO1 1/4885KMT2A 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.