Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991456 | 0.78 | POLB (0.42) | ALDH1A1TSHRALOX15CYP2D6CYP2C9 | |
| SCHEMBL20201445 | 0.76 | GRIK1 (0.38) | CYP2C19CPA1 | |
| SCHEMBL11134509 | 0.75 | ALDH1A1 (0.37) | ALDH1A1TSHRALOX15TDP1NPSR1 | |
| SCHEMBL793641 | 0.74 | ALDH1A1 (0.40) | ALDH1A1TSHRALOX15TDP1NPSR1 | |
| SCHEMBL891773 | 0.74 | CPA1 (0.42) | ALDH1A1TSHRALOX15NPSR1LMNA | |
| SCHEMBL17280333 | 0.73 | ALDH1A1 (0.57) | ALDH1A1TSHRALOX15CYP2D6CYP2C9 | |
| SCHEMBL18465494 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TSHRALOX15CYP2D6CYP2C9 | |
| SCHEMBL356446 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TSHRALOX15CYP2D6CYP2C9 | |
| SCHEMBL2878558 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TSHRALOX15CYP2D6CYP2C9 | |
| SCHEMBL8971224 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TSHRALOX15CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180147219-A1 | ENOLASE INHIBITORS AND METHODS OF TREATMENT THEREWITH | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180147219-A1 | ENOLASE INHIBITORS AND METHODS OF TREATMENT THEREWITH | ENO1, ECE1, ECI1 | ALDH1A1 488/4885TSHR 2204/4885ALOX15 2132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.