Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 7/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.42 |
| ▸ | SLC25A5 | P05141 | 2/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20201781 | 1.00 | HDAC4 (0.42) | HDAC4HDAC1HDAC6HDAC3HDAC7 | |
| SCHEMBL20201784 | 0.80 | S100A4 (0.40) | SLC25A5S100A4MAOB | |
| SCHEMBL20376450 | 0.80 | S100A4 (0.40) | SLC25A5S100A4MAOB | |
| SCHEMBL20376256 | 0.76 | S100A4 (0.39) | SLC25A5S100A4 | |
| SCHEMBL20201727 | 0.76 | S100A4 (0.39) | SLC25A5S100A4 | |
| SCHEMBL20208493 | 0.76 | S100A4 (0.39) | SLC25A5S100A4 | |
| SCHEMBL9728915 | 0.70 | S100A4 (0.40) | S100A4 | |
| SCHEMBL10440488 | 0.69 | S100A4 (0.50) | SLC25A5S100A4MAOB | |
| SCHEMBL20207026 | 0.69 | S100A4 (0.53) | SLC25A5S100A4MAOB | |
| SCHEMBL25123844 | 0.64 | HDAC8 (0.55) | HDAC4HDAC1HDAC6HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |