Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208493 | 1.00 | S100A4 (0.39) | S100A4SLC25A5CSNK2A2CSNK2A1 | |
| SCHEMBL20376256 | 1.00 | S100A4 (0.39) | S100A4SLC25A5CSNK2A2CSNK2A1 | |
| SCHEMBL20376286 | 0.86 | SLC25A5 (0.31) | SLC25A5 | |
| SCHEMBL20376450 | 0.82 | S100A4 (0.40) | S100A4SLC25A5 | |
| SCHEMBL20201784 | 0.82 | S100A4 (0.40) | S100A4SLC25A5 | |
| SCHEMBL20201723 | 0.76 | HDAC4 (0.42) | S100A4SLC25A5 | |
| SCHEMBL20201781 | 0.76 | HDAC4 (0.42) | S100A4SLC25A5 | |
| SCHEMBL20207026 | 0.70 | S100A4 (0.53) | S100A4SLC25A5CSNK2A2CSNK2A1 | |
| SCHEMBL9728915 | 0.69 | S100A4 (0.40) | S100A4 | |
| SCHEMBL10440488 | 0.68 | S100A4 (0.50) | S100A4SLC25A5CSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098208-A1 | NITROGEN RING LINKED DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |