Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.48 |
| ▸ | CHRNA5 | P30532 | 3/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204747 | 0.81 | CHRNB2 (0.67) | CHRNB2CHRNA5CHRNB4CHRNA3CNR2 | |
| SCHEMBL22751297 | 0.77 | CHRNB4 (0.43) | CHRNB2CHRNA5CHRNB4CHRNA3CNR2 | |
| SCHEMBL21325076 | 0.77 | CHRNB2 (0.43) | CHRNB2CHRNA5CHRNB4CHRNA3CNR2 | |
| SCHEMBL22432012 | 0.74 | — | — | |
| SCHEMBL20376102 | 0.72 | CHRNB2 (0.38) | CHRNB2CHRNA5CHRNB4CHRNA3CNR2 | |
| SCHEMBL28013059 | 0.67 | CNR2 (0.41) | CNR2 | |
| SCHEMBL17200005 | 0.67 | EPHX2 (0.36) | HCAR2 | |
| SCHEMBL18708222 | 0.66 | PDE4D (0.44) | CNR2 | |
| SCHEMBL9525312 | 0.66 | EPHX2 (0.38) | — | |
| SCHEMBL29011020 | 0.66 | EPHX2 (0.35) | CHRNB2CHRNA5CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |