Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.67 |
| ▸ | CHRNA5 | P30532 | 3/20 | 0.67 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.67 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.67 |
| ▸ | CNR2 | P34972 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20201749 | 0.81 | CHRNB2 (0.48) | CHRNB2CHRNA5CHRNB4CHRNA3CNR2 | |
| SCHEMBL22751297 | 0.78 | CHRNB4 (0.43) | CHRNB2CHRNA5CHRNB4CHRNA3CNR2 | |
| SCHEMBL21325076 | 0.78 | CHRNB2 (0.43) | CHRNB2CHRNA5CHRNB4CHRNA3CNR2 | |
| SCHEMBL20320518 | 0.75 | — | — | |
| SCHEMBL20201747 | 0.69 | HCAR2 (0.35) | CHRNB2CHRNA5CHRNB4CHRNA3CNR2 | |
| SCHEMBL20201745 | 0.69 | CHRNB2 (0.47) | CHRNB2CHRNA5CHRNB4CHRNA3CNR2 | |
| SCHEMBL5153799 | 0.68 | — | — | |
| SCHEMBL22432048 | 0.66 | — | — | |
| SCHEMBL6966897 | 0.66 | — | — | |
| SCHEMBL18122046 | 0.66 | ACACB (0.41) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |