Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 6/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 3/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22751405 | 0.83 | DUT (0.71) | DUTCNR2 | |
| SCHEMBL20207690 | 0.77 | DUT (0.56) | DUT | |
| SCHEMBL20207641 | 0.75 | DUT (0.55) | DUTCNR2IDH1 | |
| SCHEMBL20201788 | 0.72 | DUT (0.52) | DUT | |
| SCHEMBL172347 | 0.71 | CYP1A2 (0.49) | CNR2MEN1CYP1A2CYP2D6TSHR | |
| SCHEMBL20201798 | 0.71 | DUT (0.59) | DUT | |
| SCHEMBL20207747 | 0.71 | DUT (0.44) | DUTMEN1KMT2AIDH1 | |
| SCHEMBL10232086 | 0.70 | MMP9 (0.47) | MEN1CYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL354252 | 0.70 | MMP9 (0.47) | MEN1CYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL354251 | 0.70 | MMP9 (0.47) | MEN1CYP1A2CYP2D6TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |