Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | DUT | P33316 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22751565 | 0.79 | DUT (0.57) | ADAM17DUTACACBACACABACE1 | |
| SCHEMBL23653976 | 0.78 | ADAM17 (0.52) | ADAM17DUTACACBACACANR1H4 | |
| SCHEMBL17790227 | 0.78 | NPY1R (0.54) | SLC6A2SLC6A4 | |
| SCHEMBL20188810 | 0.78 | TLR4 (0.47) | ADAM17TLR4TLR2BACE1 | |
| SCHEMBL20377854 | 0.77 | DUT (0.49) | ADAM17DUTTLR4TLR2ACACB | |
| SCHEMBL20393533 | 0.77 | DUT (0.57) | ADAM17DUTCARM1PRMT6 | |
| SCHEMBL14017660 | 0.77 | OPRM1 (0.54) | OPRM1OPRL1SLC6A2SLC6A4 | |
| SCHEMBL22751424 | 0.76 | DUT (0.59) | ADAM17DUT | |
| SCHEMBL20374337 | 0.76 | DUT (0.50) | ADAM17DUTTLR4TLR2ACACB | |
| SCHEMBL20201717 | 0.76 | OPRM1 (0.39) | DUTOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |