Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 7/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.38 |
| ▸ | HMBS | P08397 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20376092 | 0.87 | GPR84 (0.38) | DAOHRH3HMBSSLC6A4 | |
| SCHEMBL20208260 | 0.78 | DAO (0.41) | DAOHRH3SLC6A4 | |
| SCHEMBL13117522 | 0.73 | — | — | |
| SCHEMBL23315141 | 0.72 | DAO (0.43) | DAOHRH3HMBS | |
| SCHEMBL28822944 | 0.69 | HRH3 (0.44) | DAOHRH3HMBS | |
| SCHEMBL2701611 | 0.68 | — | — | |
| SCHEMBL18521877 | 0.66 | — | — | |
| SCHEMBL3417110 | 0.65 | NPSR1 (0.47) | DAOHMBS | |
| SCHEMBL20204753 | 0.64 | HMBS (0.37) | HMBSSLC6A4 | |
| SCHEMBL9769189 | 0.64 | DAO (0.42) | DAOHRH3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |