SCHEMBL20208260

SCHEMBL20208260

CCc1c[nH]c(CCC2CC2)c1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DAO P14920 6/20 0.41
HRH3 Q9Y5N1 7/20 0.38
GPR84 Q9NQS5 1/20 0.31
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20201824 0.78 DAO (0.43) DAOHRH3SLC6A4
SCHEMBL28306543 0.77 MPO (0.34) GPR84
SCHEMBL891414 0.74
SCHEMBL20376092 0.67 GPR84 (0.38) DAOHRH3GPR84SLC6A4
SCHEMBL12097276 0.66 MPO (0.35) DAOGPR84
SCHEMBL30792639 0.66 CYP1A2 (0.35) HRH3GPR84
SCHEMBL12461863 0.66 DAO (0.37) DAO
SCHEMBL16191126 0.64 MAOB (0.44) GPR84
SCHEMBL9059518 0.64 MAOB (0.47) HRH3GPR84
SCHEMBL9059515 0.64 MAOB (0.47) HRH3GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018098208-A1 NITROGEN RING LINKED DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CV6 THERAPEUTICS (NI) LIMITED (GB) 2018-05-31 WO disclosed