Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20206761 | 0.77 | FEN1 (0.36) | HTR2AALOX5APFEN1PARP10PARP15 | |
| SCHEMBL20376466 | 0.77 | FEN1 (0.36) | HTR2AALOX5APFEN1PARP10PARP15 | |
| SCHEMBL21533978 | 0.74 | FEN1 (0.37) | ALOX5APFEN1 | |
| SCHEMBL21325344 | 0.74 | ALOX5AP (0.34) | HTR2AALOX5APFEN1 | |
| SCHEMBL21325048 | 0.74 | ALOX5AP (0.34) | HTR2AALOX5APFEN1 | |
| SCHEMBL20190174 | 0.73 | S1PR1 (0.39) | HTR2AALOX5APFEN1 | |
| SCHEMBL20201864 | 0.73 | KDM4E (0.42) | ALOX5APFEN1PARP10PARP15 | |
| SCHEMBL20204881 | 0.73 | ALOX5AP (0.35) | HTR2AALOX5APFEN1 | |
| SCHEMBL21325054 | 0.73 | ALOX5AP (0.34) | HTR2AALOX5APFEN1PARP10 | |
| SCHEMBL21690525 | 0.72 | ALOX5AP (0.32) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |