Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.35 |
| ▸ | FEN1 | P39748 | 3/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20206761 | 0.92 | FEN1 (0.36) | ALOX5APFEN1FFAR1HTR2CHTR2B | |
| SCHEMBL20376466 | 0.92 | FEN1 (0.36) | ALOX5APFEN1FFAR1HTR2CHTR2B | |
| SCHEMBL20207781 | 0.82 | ADRA1A (0.40) | ALOX5APFEN1ADRA1AHTR2CHTR2B | |
| SCHEMBL20204868 | 0.82 | ADRA1A (0.40) | ALOX5APFEN1ADRA1AHTR2CHTR2B | |
| SCHEMBL20190174 | 0.82 | S1PR1 (0.39) | ALOX5APFEN1HTR2CHTR2BHTR2A | |
| SCHEMBL20201618 | 0.82 | ALOX5AP (0.36) | ALOX5APFEN1FFAR1HTR2CHTR2B | |
| SCHEMBL21325347 | 0.82 | RIPK1 (0.34) | ALOX5APFEN1ADRA1AFFAR1HTR2C | |
| SCHEMBL21325053 | 0.82 | RIPK1 (0.34) | ALOX5APFEN1ADRA1AFFAR1HTR2C | |
| SCHEMBL21533978 | 0.77 | FEN1 (0.37) | ALOX5APFEN1FFAR1ACACB | |
| SCHEMBL21325048 | 0.77 | ALOX5AP (0.34) | ALOX5APFEN1FFAR1HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |