Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.34 |
| ▸ | FEN1 | P39748 | 4/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21325048 | 1.00 | ALOX5AP (0.34) | ALOX5APFEN1RIPK1FFAR1HTR2A | |
| SCHEMBL21325054 | 0.96 | ALOX5AP (0.34) | ALOX5APFEN1RIPK1FFAR1HTR2A | |
| SCHEMBL21325053 | 0.92 | RIPK1 (0.34) | ALOX5APFEN1RIPK1FFAR1HTR2A | |
| SCHEMBL21325347 | 0.92 | RIPK1 (0.34) | ALOX5APFEN1RIPK1FFAR1HTR2A | |
| SCHEMBL21324914 | 0.85 | FABP4 (0.37) | ALOX5APFEN1RIPK1HTR2CHTR2B | |
| SCHEMBL21533824 | 0.85 | FABP4 (0.37) | ALOX5APFEN1RIPK1HTR2CHTR2B | |
| SCHEMBL20206761 | 0.83 | FEN1 (0.36) | ALOX5APFEN1FFAR1HTR2AHTR2C | |
| SCHEMBL20376466 | 0.83 | FEN1 (0.36) | ALOX5APFEN1FFAR1HTR2AHTR2C | |
| SCHEMBL22751137 | 0.81 | FABP4 (0.39) | RIPK1HTR2CHTR2BCNR2HCRTR1 | |
| SCHEMBL21533978 | 0.80 | FEN1 (0.37) | ALOX5APFEN1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247984-B2 | Uracil containing compounds | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2022-02-15 | — | — | US | disclosed |
| US-11174271-B2 | 6-membered uracil isosteres | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2021-11-16 | — | — | US | disclosed |
| US-20200039966-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2020-02-06 | — | — | US | disclosed |
| US-20190330210-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2019-10-31 | — | — | US | disclosed |
| US-20190270756-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2019-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174271-B2 | 6-membered uracil isosteres | UNG, DUT, DPYD | ALOX5AP 3330/4885FEN1 52/4885RIPK1 3321/4885 |
| US-20190330210-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | DUT, TYMP, DPYD | ALOX5AP 2919/4885FEN1 108/4885RIPK1 3869/4885 |
| US-20200039966-A1 | URACIL CONTAINING COMPOUNDS | UNG, DPYD, DUT | ALOX5AP 2695/4885FEN1 21/4885RIPK1 3431/4885 |
| US-11247984-B2 | Uracil containing compounds | UNG, DPYD, DUT | ALOX5AP 2695/4885FEN1 21/4885RIPK1 3431/4885 |
| US-20190270756-A1 | 6-MEMBERED URACIL ISOSTERES | UNG, DUT, DPYD | ALOX5AP 3330/4885FEN1 52/4885RIPK1 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.