Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 17/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22751454 | 0.86 | DUT (0.56) | DUT | |
| SCHEMBL20201879 | 0.76 | DUT (0.40) | DUT | |
| SCHEMBL20376268 | 0.75 | DUT (0.47) | DUTROCK2 | |
| SCHEMBL22751497 | 0.74 | DUT (0.51) | DUT | |
| SCHEMBL20188140 | 0.71 | DUT (0.50) | DUT | |
| SCHEMBL20201820 | 0.71 | ADAM17 (0.45) | DUTBACE1ADAM17 | |
| SCHEMBL22723231 | 0.69 | DUT (0.56) | DUT | |
| SCHEMBL22751489 | 0.69 | DUT (0.56) | DUT | |
| SCHEMBL20201623 | 0.69 | DUT (0.56) | DUT | |
| SCHEMBL20201763 | 0.68 | DUT (0.51) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |