Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 4/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KIF5B | P33176 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21325055 | 0.83 | RIPK1 (0.33) | PIK3R1PIK3CAALOX5APFEN1RET | |
| SCHEMBL21534011 | 0.76 | HTR2C (0.36) | ALOX5APFEN1HTR2CHTR7HTR2B | |
| SCHEMBL21325050 | 0.75 | HTR2B (0.35) | ALOX5APFEN1HTR2CHTR7HTR2B | |
| SCHEMBL20204677 | 0.72 | PDE2A (0.37) | ALOX5APFEN1PDE10APDE2AFFAR4 | |
| SCHEMBL20376461 | 0.71 | CYP1A2 (0.38) | ALOX5APFEN1PDE10AHTR2CHTR7 | |
| SCHEMBL21690529 | 0.71 | ALOX5AP (0.34) | ALOX5APFEN1HTR2CHTR7HTR2B | |
| SCHEMBL21325060 | 0.70 | ALOX5AP (0.33) | ALOX5APFEN1HTR2CHTR7HTR2B | |
| SCHEMBL332545 | 0.70 | ABCB1 (0.38) | PIK3R1PIK3CARETKDR | |
| SCHEMBL21325059 | 0.69 | PDE3B (0.35) | ALOX5APFEN1HTR2CHTR7HTR2B | |
| SCHEMBL20350917 | 0.68 | PIK3CA (0.42) | PIK3R1PIK3CARETPDE10AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |