Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.33 |
| ▸ | FEN1 | P39748 | 3/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21325503 | 0.80 | FFAR4 (0.33) | FFAR4ALOX5APFEN1CHUKMAOA | |
| SCHEMBL21534011 | 0.77 | HTR2C (0.36) | FFAR4ALOX5APFEN1HTR4HTR2C | |
| SCHEMBL21690528 | 0.77 | RIPK1 (0.38) | FFAR4ALOX5APFEN1HTR4HTR2C | |
| SCHEMBL21690530 | 0.75 | FFAR4 (0.38) | FFAR4ALOX5APFEN1CHUKHTR4 | |
| SCHEMBL20376461 | 0.73 | CYP1A2 (0.38) | ALOX5APFEN1HTR4HTR2CHTR7 | |
| SCHEMBL20204677 | 0.71 | PDE2A (0.37) | FFAR4ALOX5APFEN1CHUKPDE4D | |
| SCHEMBL21325050 | 0.71 | HTR2B (0.35) | FFAR4ALOX5APFEN1HTR4HTR2C | |
| SCHEMBL21325057 | 0.70 | RIPK1 (0.37) | ALOX5APFEN1HTR4HTR2CHTR7 | |
| SCHEMBL21690529 | 0.70 | ALOX5AP (0.34) | FFAR4ALOX5APFEN1HTR4HTR2C | |
| SCHEMBL20202028 | 0.69 | PIK3R1 (0.39) | FFAR4ALOX5APFEN1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247984-B2 | Uracil containing compounds | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2022-02-15 | — | — | US | disclosed |
| US-20200039966-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2020-02-06 | — | — | US | disclosed |
| US-20190270756-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2019-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039966-A1 | URACIL CONTAINING COMPOUNDS | UNG, DPYD, DUT | PDE3B 3151/4885PDE3A 3001/4885FFAR4 4640/4885 |
| US-11247984-B2 | Uracil containing compounds | UNG, DPYD, DUT | PDE3B 3151/4885PDE3A 3001/4885FFAR4 4640/4885 |
| US-20190270756-A1 | 6-MEMBERED URACIL ISOSTERES | UNG, DUT, DPYD | PDE3B 2796/4885PDE3A 2801/4885FFAR4 4698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.