Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 5/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21690528 | 0.83 | RIPK1 (0.38) | HTR1ASLC6A2SLC6A4HTR2CHTR7 | |
| SCHEMBL21325057 | 0.82 | RIPK1 (0.37) | HTR1AHTR2CHTR7HTR2BHTR3A | |
| SCHEMBL20204677 | 0.80 | PDE2A (0.37) | ALOX5APFEN1PDE10A | |
| SCHEMBL879145 | 0.76 | RIPK1 (0.47) | CYP1A2CYP2A6HTR2CPDE10ABRD4 | |
| SCHEMBL21325059 | 0.73 | PDE3B (0.35) | HTR1AHTR2CHTR7HTR2BHTR3A | |
| SCHEMBL21325503 | 0.72 | FFAR4 (0.33) | HTR2CHTR2BHTR3AHTR4ALOX5AP | |
| SCHEMBL20202028 | 0.71 | PIK3R1 (0.39) | HTR2CHTR7HTR2BHTR3AHTR4 | |
| SCHEMBL24153922 | 0.70 | RIPK1 (0.47) | HTR1ASLC6A2SLC6A4HTR2CHTR2B | |
| SCHEMBL24180249 | 0.70 | FEN1 (0.41) | HTR1ASLC6A2SLC6A4ALOX5APFEN1 | |
| SCHEMBL8232372 | 0.70 | THRA (0.36) | HTR1ASLC6A2SLC6A4ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128720-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-07-12 | — | — | WO | disclosed |