SCHEMBL20202282

SCHEMBL20202282

C=C(C)C(=O)Oc1cc(-c2ccc(CC)c(OC(=O)C(=C)C)c2)ccc1CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 2/20 0.39
ELANE P08246 1/20 0.38
CFD P00746 1/20 0.38
HTT P42858 1/20 0.37
KMT2A Q03164 3/20 0.36
ATM Q13315 1/20 0.36
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 2/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
THRB P10828 1/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALOX5 P09917 1/20 0.33
SRD5A2 P31213 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202284 0.92 HSD17B1 (0.41) HSD17B1ELANECFDHTTKMT2A
SCHEMBL15495894 0.85 CAMK2A (0.39) HSD17B1ELANEKMT2AATM
SCHEMBL15329543 0.82 CFD (0.46) ELANECFDKMT2AATMALDH1A1
SCHEMBL22072446 0.81 ALOX15 (0.40) HSD17B1CFDALDH1A1ALOX5AKT1
SCHEMBL15338891 0.80 CFD (0.44) ELANECFDKMT2AATMALDH1A1
SCHEMBL15338874 0.80 CFD (0.44) ELANECFDKMT2AATMALDH1A1
SCHEMBL18806059 0.80 ELANE (0.47) HSD17B1ELANECFDKMT2AATM
SCHEMBL147468 0.79 ELANE (0.47) ELANEATMALDH1A1THRBKDM4E
SCHEMBL15338871 0.77 CFD (0.35) HSD17B1ELANECFDHTTKMT2A
SCHEMBL21003931 0.77 TSHR (0.47) CFDHTTMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180157174-A1 NEGATIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE TYPE PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND METHOD OF PREPARING PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2018-06-07 US disclosed
US-20180149975-A1 NEGATIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE TYPE PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND METHOD OF PREPARING PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2018-05-31 US disclosed