Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | DTYMK | P23919 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1887530 | 0.81 | TSHR (0.56) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL16123041 | 0.81 | TDP1 (0.51) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL28138122 | 0.80 | DTYMK (0.62) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL8994310 | 0.80 | TDP1 (0.58) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL29355161 | 0.80 | DTYMK (0.62) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL268279 | 0.80 | DTYMK (0.62) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL22065496 | 0.78 | ALDH1A1 (0.49) | TDP1ALDH1A1MAPK1SMN1; SMN2NPC1 | |
| SCHEMBL10773732 | 0.78 | TDP1 (0.56) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| Ammonia Solution, Strong SCHEMBL30783526 | 0.78 | DTYMK (0.60) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL267231 | 0.77 | GAA (0.58) | TSHRTDP1ALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11660350-B2 | Antibacterial products | UNIVERSITY OF LINCOLN (GB) | 2023-05-30 | — | — | US | disclosed |
| US-20180147290-A1 | NEW ANTIBACTERIAL PRODUCTS | UNIVERSITY OF LINCOLN (GB) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11660350-B2 | Antibacterial products | MSN, VAPA, SLC47A2 | TSHR 3948/4885TDP1 4761/4885ALDH1A1 4338/4885 |
| US-20180147290-A1 | NEW ANTIBACTERIAL PRODUCTS | MSN, VAPA, VAPB | TSHR 3813/4885TDP1 4789/4885ALDH1A1 4635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.