Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 8/20 | 0.81 |
| ▸ | MEN1 | O00255 | 5/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.81 |
| ▸ | HPGD | P15428 | 3/20 | 0.81 |
| ▸ | HTT | P42858 | 2/20 | 0.81 |
| ▸ | RECQL | P46063 | 2/20 | 0.81 |
| ▸ | BLM | P54132 | 2/20 | 0.81 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.81 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.81 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31580046 | 0.92 | FTO (0.66) | FTOMEN1KMT2AMAPTTDP1 | |
| SCHEMBL9610878 | 0.92 | FTO (0.66) | FTOMEN1KMT2AMAPTTDP1 | |
| Fluorescein SCHEMBL27818570 | 0.91 | FTO (0.92) | FTOMEN1KMT2AMAPTTDP1 | |
| SCHEMBL10145542 | 0.91 | FTO (0.77) | FTOMEN1KMT2AMAPTTDP1 | |
| Fluorescein SCHEMBL8648355 | 0.90 | FTO (0.94) | FTOMEN1KMT2AMAPTTDP1 | |
| Fluorescein SCHEMBL29371199 | 0.90 | FTO (1.00) | FTOMEN1KMT2AMAPTTDP1 | |
| Fluorescein SCHEMBL29388667 | 0.90 | FTO (1.00) | FTOMEN1KMT2AMAPTTDP1 | |
| Fluorescein SCHEMBL30272223 | 0.90 | FTO (1.00) | FTOMEN1KMT2AMAPTTDP1 | |
| Fluorescein SCHEMBL16533 | 0.90 | FTO (1.00) | FTOMEN1KMT2AMAPTTDP1 | |
| Fluorescein SCHEMBL3645090 | 0.90 | FTO (1.00) | FTOMEN1KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10413583-B2 | Synthetic substrates for enzymes that catalyze reactions of modified cysteines and related methods | THE UNIVERSITY OF CHICAGO (US) | 2019-09-17 | — | — | US | disclosed |
| US-20180147250-A1 | SYNTHETIC SUBSTRATES FOR ENZYMES THAT CATALYZE REACTIONS OF MODIFIED CYSTEINES AND RELATED METHODS | THE UNIVERSITY OF CHICAGO | 2018-05-31 | — | — | US | disclosed |
| US-20180147250-A1 | SYNTHETIC SUBSTRATES FOR ENZYMES THAT CATALYZE REACTIONS OF MODIFIED CYSTEINES AND RELATED METHODS | THE UNIVERSITY OF CHICAGO | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10413583-B2 | Synthetic substrates for enzymes that catalyze reactions of modified cysteines and related methods | DNPEP, PTMS, CTH | FTO 1145/4885MEN1 1884/4885KMT2A 3156/4885 |
| US-20180147250-A1 | SYNTHETIC SUBSTRATES FOR ENZYMES THAT CATALYZE REACTIONS OF MODIFIED CYSTEINES AND RELATED METHODS | DNPEP, PTMS, CTH | FTO 1145/4885MEN1 1884/4885KMT2A 3156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.