Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22168536 | 0.92 | THRB (0.40) | THRBLMNAPOLBMEN1NPC1 | |
| SCHEMBL20629507 | 0.90 | THRB (0.42) | THRBPOLBMEN1NPC1RAB9A | |
| SCHEMBL20629656 | 0.83 | THRB (0.40) | THRBPOLBMEN1NPC1RAB9A | |
| SCHEMBL26225954 | 0.83 | THRB (0.37) | THRBPOLBMEN1NPC1RAB9A | |
| SCHEMBL23230272 | 0.80 | LMNA (0.38) | THRBLMNATSHRCA1CA2 | |
| SCHEMBL20808497 | 0.79 | THRB (0.32) | THRBLMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL21949372 | 0.78 | THRB (0.33) | THRBLMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL26309242 | 0.78 | THRB (0.40) | THRBLMNATSHRSMN1; SMN2HPGD | |
| SCHEMBL20629129 | 0.76 | THRB (0.35) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL22698340 | 0.76 | THRB (0.46) | THRBLMNAPOLBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11285240-B2 | Particles | MICROVENTION, INC. (US) | 2022-03-29 | — | — | US | disclosed |
| US-20200397942-A1 | PARTICLES | MICROVENTION, INC. | 2020-12-24 | — | — | US | disclosed |
| US-10792390-B2 | Particles | MICROVENTION, INC. (US) | 2020-10-06 | — | — | US | disclosed |
| US-20200121824-A1 | PARTICLES | MICROVENTION, INC. | 2020-04-23 | — | — | US | disclosed |
| US-20190343982-A1 | PARTICLES | MICROVENTION, INC. | 2019-11-14 | — | — | US | disclosed |
| US-20180147317-A1 | PARTICLES | MICROVENTION, INC. | 2018-05-31 | — | — | US | disclosed |