Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20629507 | 0.87 | THRB (0.42) | THRBTSHRALDH1A1POLBKMT2A | |
| SCHEMBL20204440 | 0.83 | THRB (0.40) | THRBTSHRALDH1A1POLBKMT2A | |
| SCHEMBL26225954 | 0.80 | THRB (0.37) | THRBTSHRALDH1A1POLBKMT2A | |
| SCHEMBL22168536 | 0.78 | THRB (0.40) | THRBTSHRALDH1A1POLBKMT2A | |
| SCHEMBL20629129 | 0.73 | THRB (0.35) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL26309543 | 0.70 | THRB (0.43) | THRBTSHRALDH1A1POLBKMT2A | |
| SCHEMBL7054333 | 0.69 | THRB (0.41) | THRBTSHRALDH1A1POLBCA1 | |
| SCHEMBL23230272 | 0.69 | LMNA (0.38) | THRBTSHRCA1CA2 | |
| SCHEMBL13967508 | 0.68 | THRB (0.53) | THRBTSHRALDH1A1POLBCA1 | |
| SCHEMBL9720843 | 0.66 | THRB (0.50) | THRBTSHRALDH1A1POLBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137124-B1 | POLYMERS INCLUDING ACTIVE AGENTS | MICROVENTION INC (US) | 2019-01-09 | — | — | EP | disclosed |