Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 6/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | IL6 | P05231 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204886 | 0.83 | MCHR1 (0.35) | ALDH1A1IL6TLR7MEN1KMT2A | |
| SCHEMBL20204885 | 0.76 | BCHE (0.36) | ALDH1A1IL6TLR7MEN1KMT2A | |
| SCHEMBL21536671 | 0.74 | DUT (0.43) | DUTALDH1A1MAPTRORCNPC1 | |
| SCHEMBL20204633 | 0.74 | CYP2D6 (0.35) | DUTALDH1A1MEN1KMT2ABCHE | |
| SCHEMBL21536719 | 0.69 | DUT (0.43) | DUTALDH1A1NPC1 | |
| SCHEMBL21536061 | 0.66 | DUT (0.41) | DUTL3MBTL1 | |
| SCHEMBL21536675 | 0.66 | DUT (0.43) | DUTALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL21536564 | 0.64 | DUT (0.43) | DUTALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL20189396 | 0.63 | DUT (0.49) | DUTALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL20188201 | 0.63 | DUT (0.49) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |