Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | IL6 | P05231 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204886 | 0.94 | MCHR1 (0.35) | BCHENOS3NOS1NOS2KCNH2 | |
| SCHEMBL20204633 | 0.85 | CYP2D6 (0.35) | BCHENOS3NOS1NOS2KCNH2 | |
| SCHEMBL20204636 | 0.76 | CXCR4 (0.36) | BCHEMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL21536718 | 0.68 | DUT (0.43) | NPC1ALDH1A1 | |
| SCHEMBL20204894 | 0.63 | BCHE (0.40) | BCHENOS3NOS1NOS2ADRB2 | |
| SCHEMBL21536596 | 0.63 | DUT (0.43) | NPC1ALDH1A1 | |
| SCHEMBL21536566 | 0.61 | DUT (0.45) | KDM4EALDH1A1 | |
| SCHEMBL21536722 | 0.60 | DUT (0.49) | NPC1ALDH1A1 | |
| SCHEMBL5223504 | 0.59 | BCHE (0.66) | BCHEKDM4EALDH1A1 | |
| SCHEMBL5947737 | 0.58 | BCHE (0.47) | BCHENOS3NOS1NOS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |