Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21325074 | 0.77 | CNR2 (0.36) | HCAR2PARP15PARP10PARP2CNR2 | |
| SCHEMBL20208335 | 0.70 | ADORA2A (0.38) | PARP15PARP10PARP2ADORA2ABRD4 | |
| SCHEMBL20204747 | 0.69 | CHRNB2 (0.67) | HCAR2CHRNB2CHRNA5CHRNB4CHRNA3 | |
| SCHEMBL16727170 | 0.68 | LMNA (0.47) | PARP15PARP10PARP2RIPK1 | |
| SCHEMBL14943724 | 0.67 | HTR1A (0.42) | PARP15PARP10RIPK1 | |
| SCHEMBL20207973 | 0.67 | PARP15 (0.39) | HCAR2PARP15PARP10BRD4CREBBP | |
| SCHEMBL20204753 | 0.67 | HMBS (0.37) | HCAR2PARP15PARP10PARP2BRD4 | |
| SCHEMBL21350240 | 0.64 | PARP15 (0.36) | PARP15PARP10PARP2ADORA2ABRD4 | |
| SCHEMBL20201749 | 0.64 | CHRNB2 (0.48) | HCAR2CHRNB2CHRNA5CHRNB4CHRNA3 | |
| SCHEMBL8930160 | 0.64 | PARP15 (0.55) | PARP15PARP10PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |