Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21561651 | 0.73 | PDK1 (0.48) | SMN1; SMN2 | |
| SCHEMBL20204851 | 0.73 | — | — | |
| SCHEMBL21561662 | 0.73 | PDK1 (0.48) | SMN1; SMN2 | |
| SCHEMBL19096933 | 0.66 | OPRM1 (0.39) | — | |
| SCHEMBL21561707 | 0.65 | POLB (0.31) | — | |
| SCHEMBL19096873 | 0.62 | HPGD (0.50) | SMN1; SMN2 | |
| SCHEMBL20058423 | 0.62 | ALDH1A1 (0.50) | SMN1; SMN2 | |
| SCHEMBL17318831 | 0.62 | ALDH1A1 (0.50) | SMN1; SMN2 | |
| SCHEMBL13565618 | 0.62 | — | — | |
| SCHEMBL20671901 | 0.60 | SMN1; SMN2 (0.42) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098473-A1 | REAGENTS AND METHODS FOR ANALYSIS OF PROTEINS AND METABOLITES TARGETED BY COVALENT PROBES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-05-31 | — | — | WO | disclosed |