Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509976 | 0.89 | MEN1 (0.64) | MEN1POLBKMT2AL3MBTL1MAPT | |
| SCHEMBL7923572 | 0.83 | MAPT (0.59) | MEN1POLBKMT2AL3MBTL1MAPT | |
| SCHEMBL3027410 | 0.81 | CYP1A1 (0.60) | MEN1POLBKMT2AL3MBTL1MAPT | |
| SCHEMBL5804257 | 0.79 | GAA (0.63) | MEN1POLBKMT2AL3MBTL1MAPT | |
| SCHEMBL4281634 | 0.79 | POLB (0.73) | MEN1POLBKMT2AL3MBTL1MAPT | |
| SCHEMBL7934465 | 0.79 | KMT2A (0.73) | MEN1POLBKMT2AL3MBTL1MAPT | |
| SCHEMBL5804324 | 0.79 | SMN1; SMN2 (0.59) | MEN1POLBKMT2AL3MBTL1MAPT | |
| SCHEMBL7314984 | 0.79 | ALDH1A1 (0.58) | MEN1POLBKMT2AL3MBTL1MAPT | |
| SCHEMBL10698287 | 0.79 | POLB (0.50) | MEN1POLBKMT2AL3MBTL1MAPT | |
| SCHEMBL253778 | 0.78 | HDAC1 (0.65) | MEN1POLBKMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098473-A1 | REAGENTS AND METHODS FOR ANALYSIS OF PROTEINS AND METABOLITES TARGETED BY COVALENT PROBES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-05-31 | — | — | WO | disclosed |