Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PEPD | P12955 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MB | P02144 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | RARG | P13631 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509976 | 0.91 | MEN1 (0.64) | MEN1MAPTKMT2APOLBL3MBTL1 | |
| SCHEMBL27937384 | 0.82 | CYP1A1 (0.84) | CYP1A1MEN1MAPTKMT2APOLB | |
| SCHEMBL5804324 | 0.81 | SMN1; SMN2 (0.59) | CYP1A1MEN1MAPTKMT2APOLB | |
| SCHEMBL20204849 | 0.81 | MEN1 (0.55) | MEN1MAPTKMT2APOLBL3MBTL1 | |
| SCHEMBL7923572 | 0.81 | MAPT (0.59) | MEN1MAPTKMT2APOLBL3MBTL1 | |
| SCHEMBL4281634 | 0.81 | POLB (0.73) | MEN1MAPTKMT2APOLBL3MBTL1 | |
| SCHEMBL7314984 | 0.81 | ALDH1A1 (0.58) | MEN1MAPTKMT2APOLBL3MBTL1 | |
| SCHEMBL7934465 | 0.81 | KMT2A (0.73) | MEN1MAPTKMT2APOLBL3MBTL1 | |
| SCHEMBL5804257 | 0.81 | GAA (0.63) | MEN1MAPTKMT2APOLBL3MBTL1 | |
| SCHEMBL253778 | 0.80 | HDAC1 (0.65) | MEN1MAPTKMT2APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230263772-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN AND/OR INFLAMMATION | NEUMENTUM INC (US) | 2023-08-24 | — | — | US | claimed |
| EP-4136072-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN AND/OR INFLAMMATION | Neumentum, Inc. (US) | 2023-02-22 | — | — | EP | claimed |
| CN-113993846-A | Compositions and methods for treating pain and/or inflammation | 诺门图姆股份有限公司 | 2022-01-28 | — | — | CN | claimed |
| US-20220008390-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN AND/OR INFLAMMATION | NEUMENTUM, INC. | 2022-01-13 | — | — | US | claimed |
| WO-2021211681-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN AND/OR INFLAMMATION | NEUMENTUM, INC. (US) | 2021-10-21 | — | — | WO | claimed |
| WO-2005084663-A1 | HETERO-SUBSTITUTED ACETANILIDE DERIVATES AS ANALGESIC AGENTS | JANSSEN PHARMACEUTICA N.V. (US) | 2005-09-15 | — | — | WO | claimed |
| US-20050182108-A1 | or antipyretics; use of N-heterocyclecarboxylic acid, p-hydroxyphenyl amides or N-(p-hydroxyphenyl)-2-thio-group substituted acetamides; e.g. Pyrrolidine-2-carboxylic acid (p-hydroxyphenyl)-amide; substitute for aspirin in upper GI disease, aspirin allergy, bleeding disorders, clients on anticoagulants | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-08-18 | — | — | US | claimed |
| US-20230263772-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN AND/OR INFLAMMATION | NEUMENTUM INC (US) | 2023-08-24 | — | — | US | disclosed |
| EP-4136072-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN AND/OR INFLAMMATION | Neumentum, Inc. (US) | 2023-02-22 | — | — | EP | disclosed |
| CN-113993846-A | Compositions and methods for treating pain and/or inflammation | 诺门图姆股份有限公司 | 2022-01-28 | — | — | CN | disclosed |
| US-20220008390-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN AND/OR INFLAMMATION | NEUMENTUM, INC. | 2022-01-13 | — | — | US | disclosed |
| WO-2021211681-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN AND/OR INFLAMMATION | NEUMENTUM, INC. (US) | 2021-10-21 | — | — | WO | disclosed |
| EP-3108955-B1 | SELF-WETTING POROUS MEMBRANES | PALL CORP (US) | 2017-12-06 | — | — | EP | disclosed |
| US-9018241-B2 | Hetero-substituted acetanilide derivatives as analgesic agents | JANSSEN PHARMACEUTICA, NV (BE) | 2015-04-28 | — | — | US | disclosed |
| US-20130109863-A1 | HETERO-SUBSTITUTED ACETANILIDE DERIVATIVES AS ANALGESIC AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2013-05-02 | — | — | US | disclosed |
| US-8357715-B2 | Hetero-substituted acetanilide derivatives as analgesic agents | JANSSEN PHARMACEUTICA, NV (BE) | 2013-01-22 | — | — | US | disclosed |
| US-20100204284-A1 | HETERO-SUBSTITUTED ACETANILIDE DERIVATIVES AS ANALGESIC AGENTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2010-08-12 | — | — | US | disclosed |
| US-7718692-B2 | or antipyretics; use of N-heterocyclecarboxylic acid, p-hydroxyphenyl amides or N-(p-hydroxyphenyl)-2-thio-group substituted acetamides; e.g. Pyrrolidine-2-carboxylic acid (p-hydroxyphenyl)-amide; substitute for aspirin in upper GI disease, aspirin allergy, bleeding disorders, clients on anticoagulants | JANSSEN PHARMACEUTICA, N.V. (BE) | 2010-05-18 | — | — | US | disclosed |
| WO-2005084663-A1 | HETERO-SUBSTITUTED ACETANILIDE DERIVATES AS ANALGESIC AGENTS | JANSSEN PHARMACEUTICA N.V. (US) | 2005-09-15 | — | — | WO | disclosed |
| US-20050182108-A1 | or antipyretics; use of N-heterocyclecarboxylic acid, p-hydroxyphenyl amides or N-(p-hydroxyphenyl)-2-thio-group substituted acetamides; e.g. Pyrrolidine-2-carboxylic acid (p-hydroxyphenyl)-amide; substitute for aspirin in upper GI disease, aspirin allergy, bleeding disorders, clients on anticoagulants | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182108-A1 | or antipyretics; use of N-heterocyclecarboxylic acid, p-hydroxyphenyl amides or N-(p-hydroxyphenyl)-2-thio-group substituted acetamides; e.g. Pyrrolidine-2-carboxylic acid (p-hydroxyphenyl)-amide; substitute for aspirin in upper GI disease, aspirin allergy, bleeding disorders, clients on anticoagulants | HRH2, PTGS2, HRH4 | CYP1A1 563/4885MEN1 4526/4885MAPT 4684/4885 |
| US-20220008390-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN AND/OR INFLAMMATION | ADORA3, P2RX3, ADORA2A | CYP1A1 1478/4885MEN1 4866/4885MAPT 4640/4885 |
| US-20130109863-A1 | HETERO-SUBSTITUTED ACETANILIDE DERIVATIVES AS ANALGESIC AGENTS | OPRL1, OPRK1, AADAC | CYP1A1 476/4885MEN1 4468/4885MAPT 3275/4885 |
| US-20100204284-A1 | HETERO-SUBSTITUTED ACETANILIDE DERIVATIVES AS ANALGESIC AGENTS | OPRL1, OPRK1, AADAC | CYP1A1 476/4885MEN1 4468/4885MAPT 3275/4885 |
| US-20230263772-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN AND/OR INFLAMMATION | ADORA3, P2RX3, ADORA2A | CYP1A1 1478/4885MEN1 4866/4885MAPT 4640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.