Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.43 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | BRS3 | P32247 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8131937 | 0.82 | NOTUM (0.53) | NOTUMMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2608891 | 0.79 | NOTUM (0.46) | NOTUMMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL27439676 | 0.79 | NOTUM (0.53) | NOTUMMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL598119 | 0.76 | NOTUM (0.58) | NOTUMMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL14863624 | 0.76 | NOTUM (0.50) | NOTUMMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4384994 | 0.76 | NOTUM (0.50) | NOTUMMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8645551 | 0.76 | CYP19A1 (0.58) | NOTUMNPC1LMNATSHRCYP19A1 | |
| SCHEMBL5018752 | 0.76 | NOTUM (0.53) | NOTUMMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4341894 | 0.75 | NOTUM (0.78) | NOTUMMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL12989014 | 0.75 | LMNA (0.50) | NOTUMKDM4EALDH1A1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167067-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2023-06-01 | — | — | US | disclosed |
| US-11584720-B2 | Photoredox-catalyzed direct C-H functionalization of arenes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-02-21 | — | — | US | disclosed |
| US-10399947-B2 | Photoredox-catalyzed direct C—H functionalization of arenes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2019-09-03 | — | — | US | disclosed |
| US-20180148414-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584720-B2 | Photoredox-catalyzed direct C-H functionalization of arenes | PPOX, AOC2, AOC3 | NOTUM 3331/4885MEN1 4101/4885KMT2A 1406/4885 |
| US-10399947-B2 | Photoredox-catalyzed direct C—H functionalization of arenes | PPOX, AOC2, AOC3 | NOTUM 3386/4885MEN1 4005/4885KMT2A 1386/4885 |
| US-20180148414-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | PPOX, AOC2, AOC3 | NOTUM 3331/4885MEN1 4101/4885KMT2A 1406/4885 |
| US-20230167067-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | PPOX, AOC2, AOC3 | NOTUM 3331/4885MEN1 4101/4885KMT2A 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.